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Cocrystals Enhance Biopharmaceutical and Antimicrobial Properties of Norfloxacin

A solvate cocrystal of the antimicrobial norfloxacin (NFX) was formed by using isonicotinamide (INA) as a coformer with the solvent evaporation technique. The cocrystal formation was confirmed by performing solid-state characterization techniques. We evaluated the dissolution under supersaturated co...

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Detalles Bibliográficos
Autores principales: Gomes, Samantha Nascimento, Biscaia, Isabela Fanelli Barreto, Lopes, Diana Schon, Mengarda, Mariana, Murakami, Fábio Seigi, Oliveira, Paulo Renato, Bernardi, Larissa Sakis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10536922/
https://www.ncbi.nlm.nih.gov/pubmed/37765180
http://dx.doi.org/10.3390/pharmaceutics15092211