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Unlocking the Potential of Molecularly Imprinted Polydopamine in Sensing Applications

Molecularly imprinted polymers (MIPs) are synthetic receptors that mimic the specificity of biological antibody–antigen interactions. By using a “lock and key” process, MIPs selectively bind to target molecules that were used as templates during polymerization. While MIPs are typically prepared usin...

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Detalles Bibliográficos
Autores principales: Lamaoui, Abderrahman, Lahcen, Abdellatif Ait, Amine, Aziz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10536926/
https://www.ncbi.nlm.nih.gov/pubmed/37765566
http://dx.doi.org/10.3390/polym15183712
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author Lamaoui, Abderrahman
Lahcen, Abdellatif Ait
Amine, Aziz
author_facet Lamaoui, Abderrahman
Lahcen, Abdellatif Ait
Amine, Aziz
author_sort Lamaoui, Abderrahman
collection PubMed
description Molecularly imprinted polymers (MIPs) are synthetic receptors that mimic the specificity of biological antibody–antigen interactions. By using a “lock and key” process, MIPs selectively bind to target molecules that were used as templates during polymerization. While MIPs are typically prepared using conventional monomers, such as methacrylic acid and acrylamide, contemporary advancements have pivoted towards the functional potential of dopamine as a novel monomer. The overreaching goal of the proposed review is to fully unlock the potential of molecularly imprinted polydopamine (MIPda) within the realm of cutting-edge sensing applications. This review embarks by shedding light on the intricate tapestry of materials harnessed in the meticulous crafting of MIPda, endowing them with tailored properties. Moreover, we will cover the diverse sensing applications of MIPda, including its use in the detection of ions, small molecules, epitopes, proteins, viruses, and bacteria. In addition, the main synthesis methods of MIPda, including self-polymerization and electropolymerization, will be thoroughly examined. Finally, we will examine the challenges and drawbacks associated with this research field, as well as the prospects for future developments. In its entirety, this review stands as a resolute guiding compass, illuminating the path for researchers and connoisseurs alike.
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spelling pubmed-105369262023-09-29 Unlocking the Potential of Molecularly Imprinted Polydopamine in Sensing Applications Lamaoui, Abderrahman Lahcen, Abdellatif Ait Amine, Aziz Polymers (Basel) Review Molecularly imprinted polymers (MIPs) are synthetic receptors that mimic the specificity of biological antibody–antigen interactions. By using a “lock and key” process, MIPs selectively bind to target molecules that were used as templates during polymerization. While MIPs are typically prepared using conventional monomers, such as methacrylic acid and acrylamide, contemporary advancements have pivoted towards the functional potential of dopamine as a novel monomer. The overreaching goal of the proposed review is to fully unlock the potential of molecularly imprinted polydopamine (MIPda) within the realm of cutting-edge sensing applications. This review embarks by shedding light on the intricate tapestry of materials harnessed in the meticulous crafting of MIPda, endowing them with tailored properties. Moreover, we will cover the diverse sensing applications of MIPda, including its use in the detection of ions, small molecules, epitopes, proteins, viruses, and bacteria. In addition, the main synthesis methods of MIPda, including self-polymerization and electropolymerization, will be thoroughly examined. Finally, we will examine the challenges and drawbacks associated with this research field, as well as the prospects for future developments. In its entirety, this review stands as a resolute guiding compass, illuminating the path for researchers and connoisseurs alike. MDPI 2023-09-09 /pmc/articles/PMC10536926/ /pubmed/37765566 http://dx.doi.org/10.3390/polym15183712 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Lamaoui, Abderrahman
Lahcen, Abdellatif Ait
Amine, Aziz
Unlocking the Potential of Molecularly Imprinted Polydopamine in Sensing Applications
title Unlocking the Potential of Molecularly Imprinted Polydopamine in Sensing Applications
title_full Unlocking the Potential of Molecularly Imprinted Polydopamine in Sensing Applications
title_fullStr Unlocking the Potential of Molecularly Imprinted Polydopamine in Sensing Applications
title_full_unstemmed Unlocking the Potential of Molecularly Imprinted Polydopamine in Sensing Applications
title_short Unlocking the Potential of Molecularly Imprinted Polydopamine in Sensing Applications
title_sort unlocking the potential of molecularly imprinted polydopamine in sensing applications
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10536926/
https://www.ncbi.nlm.nih.gov/pubmed/37765566
http://dx.doi.org/10.3390/polym15183712
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