CRISPR/Cas9-Mediated Targeting of BPV-1-Transformed Primary Equine Sarcoid Fibroblasts

Equine sarcoids (EqS) are fibroblast-derived skin tumors associated with bovine papillomavirus 1 and 2 (BPV-1 and -2). Based on Southern blotting, the BPV-1 genome was not found to be integrated in the host cell genome, suggesting that EqS pathogenesis does not result from insertional mutagenesis. H...

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Detalles Bibliográficos
Autores principales: Monod, Anne, Koch, Christoph, Jindra, Christoph, Haspeslagh, Maarten, Howald, Denise, Wenker, Christian, Gerber, Vinzenz, Rottenberg, Sven, Hahn, Kerstin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10536948/
https://www.ncbi.nlm.nih.gov/pubmed/37766348
http://dx.doi.org/10.3390/v15091942

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