Cargando…

The Circadian Nobiletin-ROR Axis Suppresses Adipogenic Differentiation and IκBα/NF-κB Signaling in Adipocytes

Obesity is a known risk factor for metabolic diseases and is often associated with chronic inflammation in adipose tissue. We previously identified the polyethoxylated flavonoid Nobiletin (NOB) as a circadian clock modulator that directly binds to and activates the ROR receptors in the core oscillat...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Eunju, Mawatari, Kazuaki, Yoo, Seung-Hee, Chen, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10537147/
https://www.ncbi.nlm.nih.gov/pubmed/37764703
http://dx.doi.org/10.3390/nu15183919

Ejemplares similares