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The Silent Threat: Antimicrobial-Resistant Pathogens in Food-Producing Animals and Their Impact on Public Health

The emergence of antimicrobial resistance (AMR) is a global health problem without geographic boundaries. This increases the risk of complications and, thus, makes it harder to treat infections, which can result in higher healthcare costs and a greater number of deaths. Antimicrobials are often used...

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Autores principales: Almansour, Ayidh M., Alhadlaq, Meshari A., Alzahrani, Khaloud O., Mukhtar, Lenah E., Alharbi, Abdulmohsen L., Alajel, Sulaiman M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10537193/
https://www.ncbi.nlm.nih.gov/pubmed/37763971
http://dx.doi.org/10.3390/microorganisms11092127
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author Almansour, Ayidh M.
Alhadlaq, Meshari A.
Alzahrani, Khaloud O.
Mukhtar, Lenah E.
Alharbi, Abdulmohsen L.
Alajel, Sulaiman M.
author_facet Almansour, Ayidh M.
Alhadlaq, Meshari A.
Alzahrani, Khaloud O.
Mukhtar, Lenah E.
Alharbi, Abdulmohsen L.
Alajel, Sulaiman M.
author_sort Almansour, Ayidh M.
collection PubMed
description The emergence of antimicrobial resistance (AMR) is a global health problem without geographic boundaries. This increases the risk of complications and, thus, makes it harder to treat infections, which can result in higher healthcare costs and a greater number of deaths. Antimicrobials are often used to treat infections from pathogens in food-producing animals, making them a potential source of AMR. Overuse and misuse of these drugs in animal agriculture can lead to the development of AMR bacteria, which can then be transmitted to humans through contaminated food or direct contact. It is therefore essential to take multifaceted, comprehensive, and integrated measures, following the One Health approach. To address this issue, many countries have implemented regulations to limit antimicrobial use. To our knowledge, there are previous studies based on AMR in food-producing animals; however, this paper adds novelty related to the AMR pathogens in livestock, as we include the recent publications of this field worldwide. In this work, we aim to describe the most critical and high-risk AMR pathogens among food-producing animals, as a worldwide health problem. We also focus on the dissemination of AMR genes in livestock, as well as its consequences in animals and humans, and future strategies to tackle this threat.
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spelling pubmed-105371932023-09-29 The Silent Threat: Antimicrobial-Resistant Pathogens in Food-Producing Animals and Their Impact on Public Health Almansour, Ayidh M. Alhadlaq, Meshari A. Alzahrani, Khaloud O. Mukhtar, Lenah E. Alharbi, Abdulmohsen L. Alajel, Sulaiman M. Microorganisms Review The emergence of antimicrobial resistance (AMR) is a global health problem without geographic boundaries. This increases the risk of complications and, thus, makes it harder to treat infections, which can result in higher healthcare costs and a greater number of deaths. Antimicrobials are often used to treat infections from pathogens in food-producing animals, making them a potential source of AMR. Overuse and misuse of these drugs in animal agriculture can lead to the development of AMR bacteria, which can then be transmitted to humans through contaminated food or direct contact. It is therefore essential to take multifaceted, comprehensive, and integrated measures, following the One Health approach. To address this issue, many countries have implemented regulations to limit antimicrobial use. To our knowledge, there are previous studies based on AMR in food-producing animals; however, this paper adds novelty related to the AMR pathogens in livestock, as we include the recent publications of this field worldwide. In this work, we aim to describe the most critical and high-risk AMR pathogens among food-producing animals, as a worldwide health problem. We also focus on the dissemination of AMR genes in livestock, as well as its consequences in animals and humans, and future strategies to tackle this threat. MDPI 2023-08-22 /pmc/articles/PMC10537193/ /pubmed/37763971 http://dx.doi.org/10.3390/microorganisms11092127 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Almansour, Ayidh M.
Alhadlaq, Meshari A.
Alzahrani, Khaloud O.
Mukhtar, Lenah E.
Alharbi, Abdulmohsen L.
Alajel, Sulaiman M.
The Silent Threat: Antimicrobial-Resistant Pathogens in Food-Producing Animals and Their Impact on Public Health
title The Silent Threat: Antimicrobial-Resistant Pathogens in Food-Producing Animals and Their Impact on Public Health
title_full The Silent Threat: Antimicrobial-Resistant Pathogens in Food-Producing Animals and Their Impact on Public Health
title_fullStr The Silent Threat: Antimicrobial-Resistant Pathogens in Food-Producing Animals and Their Impact on Public Health
title_full_unstemmed The Silent Threat: Antimicrobial-Resistant Pathogens in Food-Producing Animals and Their Impact on Public Health
title_short The Silent Threat: Antimicrobial-Resistant Pathogens in Food-Producing Animals and Their Impact on Public Health
title_sort silent threat: antimicrobial-resistant pathogens in food-producing animals and their impact on public health
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10537193/
https://www.ncbi.nlm.nih.gov/pubmed/37763971
http://dx.doi.org/10.3390/microorganisms11092127
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