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Pyrenebutyrate Enhances the Antibacterial Effect of Peptide-Coupled Antisense Peptide Nucleic Acids in Streptococcus pyogenes

Antisense peptide nucleic acids (PNAs) inhibit bacterial growth in several infection models. Since PNAs are not spontaneously taken up by bacteria, they are often conjugated to carriers such as cell-penetrating peptides (CPPs) in order to improve translocation. Hydrophobic counterions such as pyrene...

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Detalles Bibliográficos
Autores principales: Abt, Corina, Gerlach, Lisa Marie, Bull, Jana, Jacob, Anette, Kreikemeyer, Bernd, Patenge, Nadja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10537354/
https://www.ncbi.nlm.nih.gov/pubmed/37763975
http://dx.doi.org/10.3390/microorganisms11092131

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