LncRNA like NMRK2 mRNA functions as a key molecular scaffold to enhance mitochondrial respiration of NONO-TFE3 rearranged renal cell carcinoma in an NAD(+) kinase-independent manner

BACKGROUND: NONO-TFE3 rearranged renal cell carcinoma (NONO-TFE3 rRCC) is one of a subtype of TFE3 rRCCs with high malignancy and poor prognosis. Compared with clear cell RCC, NONO-TFE3 rRCC shows a preference for mitochondrial respiration. We recently identified that the upregulation of nicotinamid...

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Detalles Bibliográficos
Autores principales: Chen, Yi, Lu, Yanwen, Yang, Lei, Ma, Wenliang, Dong, Yuhan, Zhou, Shuoming, Liu, Ning, Gan, Weidong, Li, Dongmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10537463/
https://www.ncbi.nlm.nih.gov/pubmed/37770905
http://dx.doi.org/10.1186/s13046-023-02837-4

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