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A New Paclitaxel Formulation Based on Secretome Isolated from Mesenchymal Stem Cells Shows a Significant Cytotoxic Effect on Osteosarcoma Cell Lines

Background: Osteosarcoma (OS) represents a rare cancer with an unfavorable prognosis that needs innovative treatment. The aim was to isolate a secretome from mesenchymal stem cells (MSCs) that are treated with paclitaxel (PTX)-containing microvesicles as a drug delivery system and analyze its cytoto...

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Detalles Bibliográficos
Autores principales: Banche Niclot, Alessia Giovanna Santa, Marini, Elena, Ferrero, Ivana, Barbero, Francesco, Rosso, Elena, Fenoglio, Ivana, Barge, Alessandro, Pessina, Augusto, Coccè, Valentina, Paino, Francesca, Mareschi, Katia, Fagioli, Franca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10537652/
https://www.ncbi.nlm.nih.gov/pubmed/37765308
http://dx.doi.org/10.3390/pharmaceutics15092340