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Comparative Stability Study of Polysorbate 20 and Polysorbate 80 Related to Oxidative Degradation

The surfactants polysorbate 20 (PS20) and polysorbate 80 (PS80) are utilized to stabilize protein drugs. However, concerns have been raised regarding the degradation of PSs in biologics and the potential impact on product quality. Oxidation has been identified as a prevalent degradation mechanism un...

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Detalles Bibliográficos
Autores principales:	Kozuch, Benedykt, Weber, Johanna, Buske, Julia, Mäder, Karsten, Garidel, Patrick, Diederichs, Tim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10537708/ https://www.ncbi.nlm.nih.gov/pubmed/37765302 http://dx.doi.org/10.3390/pharmaceutics15092332

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