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Identification of neoepitope reactive T-cell receptors guided by HLA-A03:01 and HLA-A11:01 immunopeptidomics

BACKGROUND: Tumor-specific mutated proteins can create immunogenic non-self, mutation-containing ‘neoepitopes’ that are attractive targets for adoptive T-cell therapies. To avoid the complexity of defining patient-specific, private neoepitopes, there has been major interest in targeting common share...

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Detalles Bibliográficos
Autores principales:	Ade, Catherine M, Sporn, Matthew J, Das, Sudipto, Yu, Zhiya, Hanada, Ken-ichi, Qi, Yue A, Maity, Tapan, Zhang, Xu, Guha, Udayan, Andresson, Thorkell, Yang, James C
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2023
Materias:	Basic Tumor Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10537849/ https://www.ncbi.nlm.nih.gov/pubmed/37758652 http://dx.doi.org/10.1136/jitc-2023-007097

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