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CRISPR-Cas9 knockout screening identifies KIAA1429 as an essential gene in Ewing sarcoma

BACKGROUND: Ewing sarcoma (ES) is an aggressive childhood bone and soft tissue cancer. KIAA1429 is one type of N6-methyladenosine (m6A) writer that plays a tumor-progressive role in various cancers, but the role of KIAA1429 in ES remains to be elucidated. The aim of the study was to investigate the...

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Detalles Bibliográficos
Autores principales:	Tan, Kezhe, Lu, Wenjie, Chen, Feng, Shi, Hao, Ma, Yingxuan, Chen, Zhou, Wu, Wei, Lv, Zhibao, Mo, Jialin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10537923/ https://www.ncbi.nlm.nih.gov/pubmed/37759224 http://dx.doi.org/10.1186/s13046-023-02828-5

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