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B7H3-targeting chimeric antigen receptor modification enhances antitumor effect of Vγ9Vδ2 T cells in glioblastoma

BACKGROUND: Glioblastoma (GBM) is a highly aggressive primary brain tumor with a poor prognosis. This study investigates the therapeutic potential of human Vγ9Vδ2 T cells in GBM treatment. The sensitivity of different glioma specimens to Vγ9Vδ2 T cell-mediated cytotoxicity is assessed using a patien...

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Detalles Bibliográficos
Autores principales: Wang, Yi, Ji, Nan, Zhang, Yang, Chu, Junsheng, Pan, Changcun, Zhang, Peng, Ma, Weiwei, Zhang, Xueguang, Xi, Jianzhong Jeff, Chen, Mingze, Zhang, Yonghui, Zhang, Liwei, Sun, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10537973/
https://www.ncbi.nlm.nih.gov/pubmed/37770968
http://dx.doi.org/10.1186/s12967-023-04514-8