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Stimulation of Potent Humoral and Cellular Immunity via Synthetic Dual-Antigen MVA-Based COVID-19 Vaccine COH04S1 in Cancer Patients Post Hematopoietic Cell Transplantation and Cellular Therapy

Hematopoietic cell transplantation (HCT) and chimeric antigen receptor (CAR)-T cell patients are immunocompromised, remain at high risk following SARS-CoV-2 infection, and are less likely than immunocompetent individuals to respond to vaccination. As part of the safety lead-in portion of a phase 2 c...

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Detalles Bibliográficos
Autores principales: Chiuppesi, Flavia, Ortega-Francisco, Sandra, Gutierrez, Miguel-Angel, Li, Jing, Ly, Minh, Faircloth, Katelyn, Mack-Onyeike, Jada, La Rosa, Corinna, Thomas, Sandra, Zhou, Qiao, Drake, Jennifer, Slape, Cynthia, Fernando, Paolo, Rida, Wasima, Kaltcheva, Teodora, Grifoni, Alba, Sette, Alessandro, Patterson, Angela, Dempsey, Shannon, Ball, Brian, Ali, Haris, Salhotra, Amandeep, Stein, Anthony, Nathwani, Nitya, Rosenzweig, Michael, Nikolaenko, Liana, Al Malki, Monzr M., Dickter, Jana, Nanayakkara, Deepa D., Puing, Alfredo, Forman, Stephen J., Taplitz, Randy A., Zaia, John A., Nakamura, Ryotaro, Wussow, Felix, Diamond, Don J., Dadwal, Sanjeet S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10538048/
https://www.ncbi.nlm.nih.gov/pubmed/37766168
http://dx.doi.org/10.3390/vaccines11091492