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Challenges of aortic valve tissue culture – maintenance of viability and extracellular matrix in the pulsatile dynamic microphysiological system
BACKGROUND: Calcific aortic valve disease (CAVD) causes an increasing health burden in the 21(st) century due to aging population. The complex pathophysiology remains to be understood to develop novel prevention and treatment strategies. Microphysiological systems (MPSs), also known as organ-on-chip...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10538250/ https://www.ncbi.nlm.nih.gov/pubmed/37770970 http://dx.doi.org/10.1186/s13036-023-00377-1 |