Challenges of aortic valve tissue culture – maintenance of viability and extracellular matrix in the pulsatile dynamic microphysiological system

BACKGROUND: Calcific aortic valve disease (CAVD) causes an increasing health burden in the 21(st) century due to aging population. The complex pathophysiology remains to be understood to develop novel prevention and treatment strategies. Microphysiological systems (MPSs), also known as organ-on-chip...

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Detalles Bibliográficos
Autores principales: Dittfeld, Claudia, Winkelkotte, Maximilian, Scheer, Anna, Voigt, Emmely, Schmieder, Florian, Behrens, Stephan, Jannasch, Anett, Matschke, Klaus, Sonntag, Frank, Tugtekin, Sems-Malte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10538250/
https://www.ncbi.nlm.nih.gov/pubmed/37770970
http://dx.doi.org/10.1186/s13036-023-00377-1

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