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Epigenetic histone modification by butyrate downregulates KIT and attenuates mast cell function

Short‐chain fatty acid butyrate is produced from the bacterial fermentation of indigestible fiber in the intestinal lumen, and it has been shown to attenuate lung inflammation in murine asthma models. Mast cells (MCs) are initiators of inflammatory response to allergens, and they play an important r...

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Detalles Bibliográficos
Autores principales: Gudneppanavar, Ravindra, Sabu Kattuman, Emma Elizabeth, Teegala, Lakshminarayan Reddy, Southard, Erik, Tummala, Ramakumar, Joe, Bina, Thodeti, Charles K., Paruchuri, Sailaja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10538265/
https://www.ncbi.nlm.nih.gov/pubmed/37603611
http://dx.doi.org/10.1111/jcmm.17924