Revisiting the truncated lamin A produced by a commonly used strain of Lmna knockout mice

The Lmna knockout mouse (Lmna(–/–)) created by Sullivan and coworkers in 1999 has been widely used to examine lamin A/C function. The knockout allele contains a deletion of Lmna intron 7–exon 11 sequences and was reported to be a null allele. Later, Jahn and coworkers discovered that the mutant alle...

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Detalles Bibliográficos
Autores principales: Kim, Joonyoung R., Kim, Paul H., Presnell, Ashley, Tu, Yiping, Young, Stephen G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10538457/
https://www.ncbi.nlm.nih.gov/pubmed/37754663
http://dx.doi.org/10.1080/19491034.2023.2262308

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10538457/
https://www.ncbi.nlm.nih.gov/pubmed/37754663
http://dx.doi.org/10.1080/19491034.2023.2262308

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