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Revisiting the truncated lamin A produced by a commonly used strain of Lmna knockout mice
The Lmna knockout mouse (Lmna(–/–)) created by Sullivan and coworkers in 1999 has been widely used to examine lamin A/C function. The knockout allele contains a deletion of Lmna intron 7–exon 11 sequences and was reported to be a null allele. Later, Jahn and coworkers discovered that the mutant alle...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10538457/ https://www.ncbi.nlm.nih.gov/pubmed/37754663 http://dx.doi.org/10.1080/19491034.2023.2262308 |