Bilateral tonic seizures probably induced by eperisone hydrochloride: a case report
Eperisone hydrochloride is a central muscle relaxant used to treat osteoporosis. Seizures are rare side effects of eperisone hydrochloride and have been previously reported in the medical literature in overdose situations but not at regular doses. This case report describes a 42-year-old male painte...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10538527/ https://www.ncbi.nlm.nih.gov/pubmed/37780713 http://dx.doi.org/10.3389/fneur.2023.1240526 |
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author | Luo, Long Yin, Jun Li, Zhigang Zhang, Wei Yuan, Ying Tang, Ying Deng, Ye Zhu, Ling |
author_facet | Luo, Long Yin, Jun Li, Zhigang Zhang, Wei Yuan, Ying Tang, Ying Deng, Ye Zhu, Ling |
author_sort | Luo, Long |
collection | PubMed |
description | Eperisone hydrochloride is a central muscle relaxant used to treat osteoporosis. Seizures are rare side effects of eperisone hydrochloride and have been previously reported in the medical literature in overdose situations but not at regular doses. This case report describes a 42-year-old male painter who developed severe bilateral tonic seizures after the initiation of eperisone hydrochloride at regular doses for low back pain. Symptoms gradually eased in the days following the discontinuation of eperisone hydrochloride and antiepileptic treatment, with no recurrence. This rare adverse drug reaction warrants clinical awareness; however, the mechanisms underlying these adverse reactions remain to be clarified. |
format | Online Article Text |
id | pubmed-10538527 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-105385272023-09-29 Bilateral tonic seizures probably induced by eperisone hydrochloride: a case report Luo, Long Yin, Jun Li, Zhigang Zhang, Wei Yuan, Ying Tang, Ying Deng, Ye Zhu, Ling Front Neurol Neurology Eperisone hydrochloride is a central muscle relaxant used to treat osteoporosis. Seizures are rare side effects of eperisone hydrochloride and have been previously reported in the medical literature in overdose situations but not at regular doses. This case report describes a 42-year-old male painter who developed severe bilateral tonic seizures after the initiation of eperisone hydrochloride at regular doses for low back pain. Symptoms gradually eased in the days following the discontinuation of eperisone hydrochloride and antiepileptic treatment, with no recurrence. This rare adverse drug reaction warrants clinical awareness; however, the mechanisms underlying these adverse reactions remain to be clarified. Frontiers Media S.A. 2023-09-14 /pmc/articles/PMC10538527/ /pubmed/37780713 http://dx.doi.org/10.3389/fneur.2023.1240526 Text en Copyright © 2023 Luo, Yin, Li, Zhang, Yuan, Tang, Deng and Zhu. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Neurology Luo, Long Yin, Jun Li, Zhigang Zhang, Wei Yuan, Ying Tang, Ying Deng, Ye Zhu, Ling Bilateral tonic seizures probably induced by eperisone hydrochloride: a case report |
title | Bilateral tonic seizures probably induced by eperisone hydrochloride: a case report |
title_full | Bilateral tonic seizures probably induced by eperisone hydrochloride: a case report |
title_fullStr | Bilateral tonic seizures probably induced by eperisone hydrochloride: a case report |
title_full_unstemmed | Bilateral tonic seizures probably induced by eperisone hydrochloride: a case report |
title_short | Bilateral tonic seizures probably induced by eperisone hydrochloride: a case report |
title_sort | bilateral tonic seizures probably induced by eperisone hydrochloride: a case report |
topic | Neurology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10538527/ https://www.ncbi.nlm.nih.gov/pubmed/37780713 http://dx.doi.org/10.3389/fneur.2023.1240526 |
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