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DOT1L Epigenetically Regulates Autophagy and Mitochondria Fusion in Cell Lines of Renal Cancer
OBJECTIVES: DOT1L, a histone methylase, is overexpression in renal cell cancer. However, the role and detailed molecular mechanism of DOT1L involved in renal cancer development remain unknown. METHODS: The inhibition of DOT1L was used by SGC0946 and short hairpin RNA silencing. Monodansylcadaverine...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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SAGE Publications
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10538554/ https://www.ncbi.nlm.nih.gov/pubmed/37365941 http://dx.doi.org/10.1177/15330338231167249 |