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Broad protective RBD heterotrimer vaccines neutralize SARS-CoV-2 including Omicron sub-variants XBB/BQ.1.1/BF.7

SARS-CoV-2 variants with severe immune evasion are a major challenge for COVID-19 prevention, especially the circulating Omicron XBB/BQ.1.1/BF.7 strains. Thus, the next-generation of broad-spectrum vaccines are urgently needed. Previously, we developed a COVID-19 protein subunit vaccine, ZF2001, bas...

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Detalles Bibliográficos
Autores principales: Zhang, Yanfang, Kang, Xinrui, Liu, Sheng, Han, Pu, Lei, Wenwen, Xu, Ke, Xu, Zepeng, Gao, Zhengrong, Zhou, Xuemei, An, Yaling, Han, Yuxuan, Liu, Kefang, Zhao, Xin, Dai, Lianpan, Wang, Peiyi, Wu, Guizhen, Qi, Jianxun, Xu, Kun, Gao, George F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10538664/
https://www.ncbi.nlm.nih.gov/pubmed/37721934
http://dx.doi.org/10.1371/journal.ppat.1011659