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UDP-glucose dehydrogenase (UGDH) in clinical oncology and cancer biology

UDP-glucose-6-dehydrogenase (UGDH) is a cytosolic, hexameric enzyme that converts UDP-glucose to UDP-glucuronic acid (UDP-GlcUA), a key reaction in hormone and xenobiotic metabolism and in the production of extracellular matrix precursors. In this review, we classify UGDH as a molecular indicator of...

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Detalles Bibliográficos
Autores principales: Price, Meghan J., Nguyen, Annee D., Byemerwa, Jovita K., Flowers, Jasmine, Baëta, César D., Goodwin, C. Rory
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10538703/
https://www.ncbi.nlm.nih.gov/pubmed/37769033
http://dx.doi.org/10.18632/oncotarget.28514

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