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Evaluation of a human mucosal tissue explant model for SARS-CoV-2 replication

With the onset of COVID-19, the development of ex vivo laboratory models became an urgent priority to study host-pathogen interactions in response to the pandemic. In this study, we aimed to establish an ex vivo mucosal tissue explant challenge model for studying SARS-CoV-2 infection and replication...

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Detalles Bibliográficos
Autores principales: Gordhan, Bhavna Gowan, Herrera, Carolina, Pillay, Azure-Dee, Seiphetlo, Thabiso, Ealand, Christopher Shawn, Machowski, Edith, Singh, Natasha, Seatholo, Ntombexolo, Otwombe, Kennedy, Lebina, Limakatso, Frise, Rebecca, Scarlatti, Gabriella, Chiodi, Francesca, Martinson, Neil, Fox, Julie, Kana, Bavesh Davandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10538748/
https://www.ncbi.nlm.nih.gov/pubmed/37769001
http://dx.doi.org/10.1371/journal.pone.0291146