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Maximizing multi-reaction dependencies provides more accurate and precise predictions of intracellular fluxes than the principle of parsimony
Intracellular fluxes represent a joint outcome of cellular transcription and translation and reflect the availability and usage of nutrients from the environment. While approaches from the constraint-based metabolic framework can accurately predict cellular phenotypes, such as growth and exchange ra...
Autores principales: | Hashemi, Seirana, Razaghi-Moghadam, Zahra, Nikoloski, Zoran |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10538754/ https://www.ncbi.nlm.nih.gov/pubmed/37721963 http://dx.doi.org/10.1371/journal.pcbi.1011489 |
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