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Maximizing multi-reaction dependencies provides more accurate and precise predictions of intracellular fluxes than the principle of parsimony

Intracellular fluxes represent a joint outcome of cellular transcription and translation and reflect the availability and usage of nutrients from the environment. While approaches from the constraint-based metabolic framework can accurately predict cellular phenotypes, such as growth and exchange ra...

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Detalles Bibliográficos
Autores principales: Hashemi, Seirana, Razaghi-Moghadam, Zahra, Nikoloski, Zoran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10538754/
https://www.ncbi.nlm.nih.gov/pubmed/37721963
http://dx.doi.org/10.1371/journal.pcbi.1011489

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