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lncRNA TUG1 regulates Smac/DIABLO expression by competitively inhibiting miR-29b and modulates the apoptosis of lens epithelial cells in age-related cataracts

BACKGROUND: As one of the early discovered long non-coding RNAs (lncRNA), taurine upregulation gene 1 (TUG1) has been widely expressed in a variety of tumors. Moreover, it promotes cell proliferation, differentiation, apoptosis, and migration. However, our understanding of its importance in the path...

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Detalles Bibliográficos
Autores principales: Sun, Miaomiao, Li, Ke, Li, Xiao, Wang, Huajun, Li, Li, Zheng, Guangying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10538928/
https://www.ncbi.nlm.nih.gov/pubmed/37185343
http://dx.doi.org/10.1097/CM9.0000000000002530

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