Cargando…

Myocardial perfusion and flow reserve in the asynchronous heart: mechanistic insight from a computational model

The tight coupling between myocardial oxygen demand and supply has been recognized for decades, but it remains controversial whether this coupling persists under asynchronous activation, such as during left bundle branch block (LBBB). Furthermore, it is unclear whether the amount of local cardiac wa...

Descripción completa

Detalles Bibliográficos
Autores principales:	Munneke, Anneloes G., Lumens, Joost, Arts, Theo, Prinzen, Frits W., Delhaas, Tammo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Physiological Society 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10538979/ https://www.ncbi.nlm.nih.gov/pubmed/37439238 http://dx.doi.org/10.1152/japplphysiol.00181.2023

Ejemplares similares

A Closed-Loop Modeling Framework for Cardiac-to-Coronary Coupling
por: Munneke, Anneloes G., et al.
Publicado: (2022)

Fast Simulation of Mechanical Heterogeneity in the Electrically Asynchronous Heart Using the MultiPatch Module
por: Walmsley, John, et al.
Publicado: (2015)

Mechano-energetics of the asynchronous and resynchronized heart
por: Prinzen, Frits W., et al.
Publicado: (2010)

High tension in sarcomeres hinders myocardial relaxation: A computational study
por: Dupuis, Lauren J., et al.
Publicado: (2018)

Erratum to: Mechano-energetics of the asynchronous and resynchronized heart
por: Prinzen, Frits W., et al.
Publicado: (2011)

Control of Whole Heart Geometry by Intramyocardial Mechano-Feedback: A Model Study
por: Arts, Theo, et al.
Publicado: (2012)

Three-Wall Segment (TriSeg) Model Describing Mechanics and Hemodynamics of Ventricular Interaction
por: Lumens, Joost, et al.
Publicado: (2009)

Mechano-chemical Interactions in Cardiac Sarcomere Contraction: A Computational Modeling Study
por: Dupuis, Lauren J., et al.
Publicado: (2016)

Large vessels as a tree of transmission lines incorporated in the CircAdapt whole-heart model: A computational tool to examine heart-vessel interaction
por: Heusinkveld, Maarten H. G., et al.
Publicado: (2019)

Impact of Estimated Left Atrial Pressure on Cardiac Resynchronization Therapy Outcome
por: Beela, Ahmed S., et al.
Publicado: (2023)

Modeling Cardiac Electromechanics and Mechanoelectrical Coupling in Dyssynchronous and Failing Hearts: Insight from Adaptive Computer Models
por: Kuijpers, Nico H. L., et al.
Publicado: (2012)

The Left and Right Ventricles Respond Differently to Variation of Pacing Delays in Cardiac Resynchronization Therapy: A Combined Experimental- Computational Approach
por: Willemen, Erik, et al.
Publicado: (2019)

Augmentation index is not a proxy for wave reflection magnitude: mechanistic analysis using a computational model
por: Heusinkveld, Maarten H. G., et al.
Publicado: (2019)

Chronic ventricular pacing in children: toward prevention of pacing-induced heart disease
por: van Geldorp, Irene E., et al.
Publicado: (2010)

Comparison of novel ventricular pacing strategies using an electro-mechanical simulation platform
por: Meiburg, Roel, et al.
Publicado: (2023)

Hemodynamics-driven mathematical model of first and second heart sound generation
por: Shahmohammadi, Mehrdad, et al.
Publicado: (2021)

Relative Impact of Right Ventricular Electromechanical Dyssynchrony Versus Pulmonary Regurgitation on Right Ventricular Dysfunction and Exercise Intolerance in Patients After Repair of Tetralogy of Fallot
por: Lumens, Joost, et al.
Publicado: (2019)

A Lumped Two-Compartment Model for Simulation of Ventricular Pump and Tissue Mechanics in Ischemic Heart Disease
por: Koopsen, Tijmen, et al.
Publicado: (2022)

Electro-energetics of Biventricular, Septal and Conduction System Pacing
por: Prinzen, Frits W, et al.
Publicado: (2021)

Erratum to: Electro-energetics of Biventricular, Septal and Conduction System Pacing
por: Prinzen, Frits W, et al.
Publicado: (2023)

Hemodynamics-driven mathematical model of third heart sound generation
por: Shahmohammadi, Mehrdad, et al.
Publicado: (2022)

Fractional Flow Reserve or Coronary Flow Reserve for the Assessment of Myocardial Perfusion: Implications of FFR as an Imperfect Reference Standard for Myocardial Ischemia
por: Stegehuis, Valérie E., et al.
Publicado: (2018)

1.5 and 3 Tesla quantification of myocardial perfusion reserve in comparison to fractional flow reserve
por: Bernhardt, Peter, et al.
Publicado: (2013)

Increased myocardial stiffness more than impaired relaxation function limits cardiac performance during exercise in heart failure with preserved ejection fraction: a virtual patient study
por: van Loon, Tim, et al.
Publicado: (2020)

Role of sex hormones in modulating myocardial perfusion and coronary flow reserve
por: Haider, Ahmed, et al.
Publicado: (2022)

Does heart-type fatty acid-binding protein predict clinical outcomes after pediatric cardiac surgery?
por: Evers, Egmond S, et al.
Publicado: (2017)

To what extent are perfusion defects seen by myocardial perfusion SPECT in patients with left bundle branch block related to myocardial infarction, ECG characteristics, and myocardial wall motion?
por: Hedeer, Fredrik, et al.
Publicado: (2020)

Atrioventricular dromotropathy: an important substrate for complete resynchronization therapy—Authors’ reply
por: Salden, Floor C W M, et al.
Publicado: (2022)

Smartphone as an electronic stethoscope: factors influencing heart sound quality( )
por: Luo, Hongxing, et al.
Publicado: (2022)

Myocardial perfusion MRI compared to fractional flow reserve: a meta-analysis
por: Takx, Richard, et al.
Publicado: (2015)

Association between phonocardiography and echocardiography in heart failure patients with preserved ejection fraction
por: Luo, Hongxing, et al.
Publicado: (2022)

Left Ventricular Pressure Estimation Using Machine Learning-Based Heart Sound Classification
por: Westphal, Philip, et al.
Publicado: (2022)

Second heart sound splitting as an indicator of interventricular mechanical dyssynchrony using a novel splitting detection algorithm
por: Luo, Hongxing, et al.
Publicado: (2021)

Long-term protection and mechanism of pacing-induced postconditioning in the heart
por: Babiker, Fawzi A., et al.
Publicado: (2010)

Mechanical and hemodynamic effects of left bundle branch area versus biventricular pacing in virtual heart failure patients with left bundle branch block
por: Meiburg, R, et al.
Publicado: (2023)

Myocardial perfusion reserve compared with peripheral perfusion reserve: A [13N]ammonia PET study
por: Scholtens, A. M., et al.
Publicado: (2011)

Determinants of biventricular cardiac function: a mathematical model study on geometry and myofiber orientation
por: Pluijmert, Marieke, et al.
Publicado: (2016)

Validation of myocardial perfusion quantification by dynamic CT in an ex-vivo porcine heart model
por: Pelgrim, Gert Jan, et al.
Publicado: (2017)

Asynchronicity of Facial Blood Perfusion in Migraine
por: Zaproudina, Nina, et al.
Publicado: (2013)

Successful ablation of atrial fibrillation does not normalise left ventricular function, reverse impaired myocardial energetics or increase perfusion reserve: novel mechanistic insights with clinical implications
por: Wijesurendra, Rohan S, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_foa8ho4dgggdt3252ukuf2op5a