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Pten knockout affects drug resistance differently in melanoma and kidney cancer

BACKGROUND: PTEN is a tumor suppressor that is often mutated and nonfunctional in many types of cancer. The high heterogeneity of PTEN function between tumor types makes new Pten knockout models necessary to assess its impact on cancer progression and/or treatment outcomes. METHODS: We aimed to show...

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Detalles Bibliográficos
Autores principales: Brodaczewska, Klaudia, Majewska, Aleksandra, Filipiak-Duliban, Aleksandra, Kieda, Claudine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10539195/
https://www.ncbi.nlm.nih.gov/pubmed/37673853
http://dx.doi.org/10.1007/s43440-023-00523-y