Rapid Remission of Sunburn-Induced Guttate Psoriasis with Guselkumab

Guselkumab is an anti-interleukin-23 monoclonal antibody that is approved for plaque psoriasis and psoriatic arthritis. We present a case of a 28-year-old female patient with acute onset of guttate psoriasis after a blistering sunburn. She had no personal or family history of psoriasis or chronic in...

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Autores principales: Bartholomew, Erin, Chung, Bo-Young, Davis, Mitchell, Yeroushalmi, Samuel, Chung, Mimi, Hakimi, Marwa, Bhutani, Tina, Liao, Wilson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10539232/
https://www.ncbi.nlm.nih.gov/pubmed/37676470
http://dx.doi.org/10.1007/s13555-023-01013-y
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author Bartholomew, Erin
Chung, Bo-Young
Davis, Mitchell
Yeroushalmi, Samuel
Chung, Mimi
Hakimi, Marwa
Bhutani, Tina
Liao, Wilson
author_facet Bartholomew, Erin
Chung, Bo-Young
Davis, Mitchell
Yeroushalmi, Samuel
Chung, Mimi
Hakimi, Marwa
Bhutani, Tina
Liao, Wilson
author_sort Bartholomew, Erin
collection PubMed
description Guselkumab is an anti-interleukin-23 monoclonal antibody that is approved for plaque psoriasis and psoriatic arthritis. We present a case of a 28-year-old female patient with acute onset of guttate psoriasis after a blistering sunburn. She had no personal or family history of psoriasis or chronic inflammatory skin disease. The guttate psoriasis was refractory to topical treatment. After the first dose of guselkumab (100 mg subcutaneous injection), the patient experienced near-clearance of her guttate psoriasis, with continued improvement and drug-free remission 8 months after cessation of treatment. Dermatologists could consider guselkumab as a treatment option for patients with guttate psoriasis. Future studies should examine the potential for guselkumab to induce drug-free remissions in guttate psoriasis.
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spelling pubmed-105392322023-09-30 Rapid Remission of Sunburn-Induced Guttate Psoriasis with Guselkumab Bartholomew, Erin Chung, Bo-Young Davis, Mitchell Yeroushalmi, Samuel Chung, Mimi Hakimi, Marwa Bhutani, Tina Liao, Wilson Dermatol Ther (Heidelb) Case Report Guselkumab is an anti-interleukin-23 monoclonal antibody that is approved for plaque psoriasis and psoriatic arthritis. We present a case of a 28-year-old female patient with acute onset of guttate psoriasis after a blistering sunburn. She had no personal or family history of psoriasis or chronic inflammatory skin disease. The guttate psoriasis was refractory to topical treatment. After the first dose of guselkumab (100 mg subcutaneous injection), the patient experienced near-clearance of her guttate psoriasis, with continued improvement and drug-free remission 8 months after cessation of treatment. Dermatologists could consider guselkumab as a treatment option for patients with guttate psoriasis. Future studies should examine the potential for guselkumab to induce drug-free remissions in guttate psoriasis. Springer Healthcare 2023-09-07 /pmc/articles/PMC10539232/ /pubmed/37676470 http://dx.doi.org/10.1007/s13555-023-01013-y Text en © The Author(s) 2023 https://creativecommons.org/licenses/by-nc/4.0/Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, which permits any non-commercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) .
spellingShingle Case Report
Bartholomew, Erin
Chung, Bo-Young
Davis, Mitchell
Yeroushalmi, Samuel
Chung, Mimi
Hakimi, Marwa
Bhutani, Tina
Liao, Wilson
Rapid Remission of Sunburn-Induced Guttate Psoriasis with Guselkumab
title Rapid Remission of Sunburn-Induced Guttate Psoriasis with Guselkumab
title_full Rapid Remission of Sunburn-Induced Guttate Psoriasis with Guselkumab
title_fullStr Rapid Remission of Sunburn-Induced Guttate Psoriasis with Guselkumab
title_full_unstemmed Rapid Remission of Sunburn-Induced Guttate Psoriasis with Guselkumab
title_short Rapid Remission of Sunburn-Induced Guttate Psoriasis with Guselkumab
title_sort rapid remission of sunburn-induced guttate psoriasis with guselkumab
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10539232/
https://www.ncbi.nlm.nih.gov/pubmed/37676470
http://dx.doi.org/10.1007/s13555-023-01013-y
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