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Dermatology Life Quality Index in Thai Patients with Facial Port-Wine Stains

INTRODUCTION: Port-wine stains (PWS) are congenital capillary abnormalities caused by immature, venule-like vasculature that progressively dilates due to poor endothelial cell differentiation. PWS affects between 0.3% and 0.9% of newborns, with 90% of cases occurring on the face. Individuals with fa...

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Autores principales: Jantarakolica, Tatre, Wanitphakdeedecha, Rungsima, Yan, Chadakan, Yogya, Yuri, Manuskiatti, Woraphong, Sudhipongpracha, Tatchalerm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10539252/
https://www.ncbi.nlm.nih.gov/pubmed/37710079
http://dx.doi.org/10.1007/s13555-023-01011-0
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author Jantarakolica, Tatre
Wanitphakdeedecha, Rungsima
Yan, Chadakan
Yogya, Yuri
Manuskiatti, Woraphong
Sudhipongpracha, Tatchalerm
author_facet Jantarakolica, Tatre
Wanitphakdeedecha, Rungsima
Yan, Chadakan
Yogya, Yuri
Manuskiatti, Woraphong
Sudhipongpracha, Tatchalerm
author_sort Jantarakolica, Tatre
collection PubMed
description INTRODUCTION: Port-wine stains (PWS) are congenital capillary abnormalities caused by immature, venule-like vasculature that progressively dilates due to poor endothelial cell differentiation. PWS affects between 0.3% and 0.9% of newborns, with 90% of cases occurring on the face. Individuals with facial PWS and their parents had a significant negative impairment on their quality of life (QoL) and also suffered from psychological disabilities. METHODS: This was a cross-sectional questionnaire-based survey study in Thailand from July 2021 to April 2022. The questionnaires included demographic data, subjective evaluation (SE), and the Dermatology Life Quality Index (DLQI). The questionnaire was performed with a full scale and adjusted scale of validity and reliability test of DLQI using factor analysis and Cronbach’s alpha. The study outcome was a subjective evaluation and DLQI in patients who received pulsed dye laser (PDL) treatment. RESULTS: Of the 54 patients, 35.2% (19) are male, and 64.8% (35) are female. Regarding age groups, 64.8% (35) are below 5 years old, and 35.2% (19) are older than 5 years. SE results showed that males evaluated an improvement of the facial PWS lesion significantly better than females (P < 0.05). The older age group graded the percentage of improvement better than the younger age group (P < 0.01). The result of the DLQI showed no difference in DLQI between gender. Older age result resulted in a significantly different DLQI compared with younger age (P < 0.01). Parent-reported DLQI improvement was less than self-reported DLQI improvement in patients with PWS treated with PDL (P < 0.05). Concerning the instrument of the study, the validity and reliability analysis of the DLQI questionnaire using factor analysis and Cronbach’s alpha have been performed. The adjusted scale with the 5-item DLQI questionnaire is more appropriate in terms validity and reliability. CONCLUSION: This study demonstrates that facial PWS reduces the QoL as measured by DLQI. We discovered that the QoL of patients and parents with PWS was significantly impaired. The main influencing factors were older age, the improved perception between gender, and PDL treatments. In addition, we found only five questions that are reliable for PWS. The adjusted five-item DLQI questionnaires are more appropriate regarding validity and reliability. TRIAL REGISTRATION NUMBER: TCTR20230210001, COA no. si 1059/2020.
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spelling pubmed-105392522023-09-30 Dermatology Life Quality Index in Thai Patients with Facial Port-Wine Stains Jantarakolica, Tatre Wanitphakdeedecha, Rungsima Yan, Chadakan Yogya, Yuri Manuskiatti, Woraphong Sudhipongpracha, Tatchalerm Dermatol Ther (Heidelb) Original Research INTRODUCTION: Port-wine stains (PWS) are congenital capillary abnormalities caused by immature, venule-like vasculature that progressively dilates due to poor endothelial cell differentiation. PWS affects between 0.3% and 0.9% of newborns, with 90% of cases occurring on the face. Individuals with facial PWS and their parents had a significant negative impairment on their quality of life (QoL) and also suffered from psychological disabilities. METHODS: This was a cross-sectional questionnaire-based survey study in Thailand from July 2021 to April 2022. The questionnaires included demographic data, subjective evaluation (SE), and the Dermatology Life Quality Index (DLQI). The questionnaire was performed with a full scale and adjusted scale of validity and reliability test of DLQI using factor analysis and Cronbach’s alpha. The study outcome was a subjective evaluation and DLQI in patients who received pulsed dye laser (PDL) treatment. RESULTS: Of the 54 patients, 35.2% (19) are male, and 64.8% (35) are female. Regarding age groups, 64.8% (35) are below 5 years old, and 35.2% (19) are older than 5 years. SE results showed that males evaluated an improvement of the facial PWS lesion significantly better than females (P < 0.05). The older age group graded the percentage of improvement better than the younger age group (P < 0.01). The result of the DLQI showed no difference in DLQI between gender. Older age result resulted in a significantly different DLQI compared with younger age (P < 0.01). Parent-reported DLQI improvement was less than self-reported DLQI improvement in patients with PWS treated with PDL (P < 0.05). Concerning the instrument of the study, the validity and reliability analysis of the DLQI questionnaire using factor analysis and Cronbach’s alpha have been performed. The adjusted scale with the 5-item DLQI questionnaire is more appropriate in terms validity and reliability. CONCLUSION: This study demonstrates that facial PWS reduces the QoL as measured by DLQI. We discovered that the QoL of patients and parents with PWS was significantly impaired. The main influencing factors were older age, the improved perception between gender, and PDL treatments. In addition, we found only five questions that are reliable for PWS. The adjusted five-item DLQI questionnaires are more appropriate regarding validity and reliability. TRIAL REGISTRATION NUMBER: TCTR20230210001, COA no. si 1059/2020. Springer Healthcare 2023-09-14 /pmc/articles/PMC10539252/ /pubmed/37710079 http://dx.doi.org/10.1007/s13555-023-01011-0 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by-nc/4.0/Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, which permits any non-commercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) .
spellingShingle Original Research
Jantarakolica, Tatre
Wanitphakdeedecha, Rungsima
Yan, Chadakan
Yogya, Yuri
Manuskiatti, Woraphong
Sudhipongpracha, Tatchalerm
Dermatology Life Quality Index in Thai Patients with Facial Port-Wine Stains
title Dermatology Life Quality Index in Thai Patients with Facial Port-Wine Stains
title_full Dermatology Life Quality Index in Thai Patients with Facial Port-Wine Stains
title_fullStr Dermatology Life Quality Index in Thai Patients with Facial Port-Wine Stains
title_full_unstemmed Dermatology Life Quality Index in Thai Patients with Facial Port-Wine Stains
title_short Dermatology Life Quality Index in Thai Patients with Facial Port-Wine Stains
title_sort dermatology life quality index in thai patients with facial port-wine stains
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10539252/
https://www.ncbi.nlm.nih.gov/pubmed/37710079
http://dx.doi.org/10.1007/s13555-023-01011-0
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