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NLRP6 potentiates PI3K/AKT signalling by promoting autophagic degradation of p85α to drive tumorigenesis
The PI3K/AKT pathway plays an essential role in tumour development. NOD-like receptors (NLRs) regulate innate immunity and are implicated in cancer, but whether they are involved in PI3K/AKT pathway regulation is poorly understood. Here, we report that NLRP6 potentiates the PI3K/AKT pathway by bindi...
Autores principales: | Zhi, Feng, Li, Bowen, Zhang, Chuanxia, Xia, Fan, Wang, Rong, Xie, Weihong, Cai, Sihui, Zhang, Dawei, Kong, Ren, Hu, Yiqiao, Yang, Yilin, Peng, Ya, Cui, Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10539329/ https://www.ncbi.nlm.nih.gov/pubmed/37770465 http://dx.doi.org/10.1038/s41467-023-41739-z |
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