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NLRP6 potentiates PI3K/AKT signalling by promoting autophagic degradation of p85α to drive tumorigenesis

The PI3K/AKT pathway plays an essential role in tumour development. NOD-like receptors (NLRs) regulate innate immunity and are implicated in cancer, but whether they are involved in PI3K/AKT pathway regulation is poorly understood. Here, we report that NLRP6 potentiates the PI3K/AKT pathway by bindi...

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Detalles Bibliográficos
Autores principales:	Zhi, Feng, Li, Bowen, Zhang, Chuanxia, Xia, Fan, Wang, Rong, Xie, Weihong, Cai, Sihui, Zhang, Dawei, Kong, Ren, Hu, Yiqiao, Yang, Yilin, Peng, Ya, Cui, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10539329/ https://www.ncbi.nlm.nih.gov/pubmed/37770465 http://dx.doi.org/10.1038/s41467-023-41739-z

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