Menthol- and thymol-based ciprofloxacin derivatives against Mycobacterium tuberculosis: in vitro activity, lipophilicity, and computational studies

In this work, we investigated the antitubercular properties of Ciprofloxacin derivatives conjugated with menthol and thymol moieties. For the sixteen derivatives, we established minimal inhibitory concentrations (MIC) using isolates of Mycobacterium tuberculosis that were resistant or susceptible to...

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Detalles Bibliográficos
Autores principales: Szulczyk, Daniel, Woziński, Mateusz, Koliński, Michał, Kmiecik, Sebastian, Głogowska, Agnieszka, Augustynowicz-Kopeć, Ewa, Dobrowolski, Michał A., Roszkowski, Piotr, Struga, Marta, Ciura, Krzesimir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10539350/
https://www.ncbi.nlm.nih.gov/pubmed/37770610
http://dx.doi.org/10.1038/s41598-023-43708-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10539350/
https://www.ncbi.nlm.nih.gov/pubmed/37770610
http://dx.doi.org/10.1038/s41598-023-43708-4

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