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Polygenic risk scores of lithium response and treatment resistance in major depressive disorder

Treatment response and resistance in major depressive disorder (MDD) are suggested to be heritable. Due to significant challenges in defining treatment-related phenotypes, our understanding of their genetic bases is limited. This study aimed to derive a stringent definition of treatment resistance a...

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Detalles Bibliográficos
Autores principales: Xiong, Ying, Karlsson, Robert, Song, Jie, Kowalec, Kaarina, Rück, Christian, Sigström, Robert, Jonsson, Lina, Clements, Caitlin C., Andersson, Evelyn, Boberg, Julia, Lewis, Cathryn M., Sullivan, Patrick F., Landén, Mikael, Lu, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10539379/
https://www.ncbi.nlm.nih.gov/pubmed/37770441
http://dx.doi.org/10.1038/s41398-023-02602-3