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Contribution of central sleep apnea to severe sleep apnea hypopnea syndrome
PURPOSE: Central sleep apnea (CSA) is usually distinguished from obstructive sleep apnea (OSA). In fact, CSA is often a component of severe sleep apnea hypopnea syndrome (SAHS), rather than occurring alone. We investigated the clinical characteristics and polysomnography (PSG) parameters of CSA comp...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10539457/ https://www.ncbi.nlm.nih.gov/pubmed/36849673 http://dx.doi.org/10.1007/s11325-023-02776-6 |
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author | Zhang, Guoxin Zhao, Xiaoyun Zhao, Fang Tan, Jin Zhang, Qiang |
author_facet | Zhang, Guoxin Zhao, Xiaoyun Zhao, Fang Tan, Jin Zhang, Qiang |
author_sort | Zhang, Guoxin |
collection | PubMed |
description | PURPOSE: Central sleep apnea (CSA) is usually distinguished from obstructive sleep apnea (OSA). In fact, CSA is often a component of severe sleep apnea hypopnea syndrome (SAHS), rather than occurring alone. We investigated the clinical characteristics and polysomnography (PSG) parameters of CSA components in patients with severe SAHS. METHODS: The clinical characteristics and PSG parameters were retrospectively analyzed. RESULTS: Pure or dominant CSA was rare (5% of all patients). Of all patients with CSA, 72% also exhibited other apnea subtypes that contributed to severe SAHS. Among patients with severe SAHS, those with CSA were more likely than others to be older; thinner; exhibit higher prevalences of comorbid coronary heart disease, arrhythmia, and heart failure; a higher apnea/hypopnea index (AHI); mixed apnea index (MAI); an elevated oxygen desaturation index (ODI); and more nighttime oxygen saturation levels < 90%. Multivariate logistic regression analysis revealed that older age, comorbid arrhythmia or heart failure, and an elevated ODI were independently associated with CSA. CONCLUSION: Patients who complain of snoring or apnea may be better evaluated by comprehensive PSG prior to treatment if they are old, show greater hypoxia, or suffer from arrhythmia and/or heart failure, because such patients are more likely than others to exhibit CSA. |
format | Online Article Text |
id | pubmed-10539457 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Springer International Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-105394572023-09-30 Contribution of central sleep apnea to severe sleep apnea hypopnea syndrome Zhang, Guoxin Zhao, Xiaoyun Zhao, Fang Tan, Jin Zhang, Qiang Sleep Breath Sleep Breathing Physiology and Disorders • Original Article PURPOSE: Central sleep apnea (CSA) is usually distinguished from obstructive sleep apnea (OSA). In fact, CSA is often a component of severe sleep apnea hypopnea syndrome (SAHS), rather than occurring alone. We investigated the clinical characteristics and polysomnography (PSG) parameters of CSA components in patients with severe SAHS. METHODS: The clinical characteristics and PSG parameters were retrospectively analyzed. RESULTS: Pure or dominant CSA was rare (5% of all patients). Of all patients with CSA, 72% also exhibited other apnea subtypes that contributed to severe SAHS. Among patients with severe SAHS, those with CSA were more likely than others to be older; thinner; exhibit higher prevalences of comorbid coronary heart disease, arrhythmia, and heart failure; a higher apnea/hypopnea index (AHI); mixed apnea index (MAI); an elevated oxygen desaturation index (ODI); and more nighttime oxygen saturation levels < 90%. Multivariate logistic regression analysis revealed that older age, comorbid arrhythmia or heart failure, and an elevated ODI were independently associated with CSA. CONCLUSION: Patients who complain of snoring or apnea may be better evaluated by comprehensive PSG prior to treatment if they are old, show greater hypoxia, or suffer from arrhythmia and/or heart failure, because such patients are more likely than others to exhibit CSA. Springer International Publishing 2023-02-28 2023 /pmc/articles/PMC10539457/ /pubmed/36849673 http://dx.doi.org/10.1007/s11325-023-02776-6 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/ Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Sleep Breathing Physiology and Disorders • Original Article Zhang, Guoxin Zhao, Xiaoyun Zhao, Fang Tan, Jin Zhang, Qiang Contribution of central sleep apnea to severe sleep apnea hypopnea syndrome |
title | Contribution of central sleep apnea to severe sleep apnea hypopnea syndrome |
title_full | Contribution of central sleep apnea to severe sleep apnea hypopnea syndrome |
title_fullStr | Contribution of central sleep apnea to severe sleep apnea hypopnea syndrome |
title_full_unstemmed | Contribution of central sleep apnea to severe sleep apnea hypopnea syndrome |
title_short | Contribution of central sleep apnea to severe sleep apnea hypopnea syndrome |
title_sort | contribution of central sleep apnea to severe sleep apnea hypopnea syndrome |
topic | Sleep Breathing Physiology and Disorders • Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10539457/ https://www.ncbi.nlm.nih.gov/pubmed/36849673 http://dx.doi.org/10.1007/s11325-023-02776-6 |
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