Murine cytomegalovirus downregulates ERAAP and induces an unconventional T cell response to self

The endoplasmic reticulum aminopeptidase associated with antigen processing (ERAAP) plays a crucial role in shaping the peptide-major histocompatibility complex (MHC) class I repertoire and maintaining immune surveillance. While murine cytomegalovirus (MCMV) has multiple strategies for manipulating...

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Detalles Bibliográficos
Autores principales: Geiger, Kristina M., Manoharan, Michael, Coombs, Rachel, Arana, Kathya, Park, Chan-Su, Lee, Angus Y., Shastri, Nilabh, Robey, Ellen A., Coscoy, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10539480/
https://www.ncbi.nlm.nih.gov/pubmed/36995940
http://dx.doi.org/10.1016/j.celrep.2023.112317

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10539480/
https://www.ncbi.nlm.nih.gov/pubmed/36995940
http://dx.doi.org/10.1016/j.celrep.2023.112317

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