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Murine cytomegalovirus downregulates ERAAP and induces an unconventional T cell response to self
The endoplasmic reticulum aminopeptidase associated with antigen processing (ERAAP) plays a crucial role in shaping the peptide-major histocompatibility complex (MHC) class I repertoire and maintaining immune surveillance. While murine cytomegalovirus (MCMV) has multiple strategies for manipulating...
Autores principales: | Geiger, Kristina M., Manoharan, Michael, Coombs, Rachel, Arana, Kathya, Park, Chan-Su, Lee, Angus Y., Shastri, Nilabh, Robey, Ellen A., Coscoy, Laurent |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10539480/ https://www.ncbi.nlm.nih.gov/pubmed/36995940 http://dx.doi.org/10.1016/j.celrep.2023.112317 |
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