HECW2 promotes the progression and chemoresistance of colorectal cancer via AKT/mTOR signaling activation by mediating the ubiquitin-proteasome degradation of lamin B1

Colorectal cancer (CRC) is among the most common malignancies worldwide. Although a recent study has shown that E3 ubiquitin ligases play a major role in regulating the occurrence and development of CRC, there are few reports on the role of the E3 ubiquitin ligase HECW2(HECT, C2 and WW domain contai...

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Detalles Bibliográficos
Autores principales: Li, Fang, Wang, Li, Wang, Yujue, Shen, Hui, Kou, Qianrui, Shen, Changjun, Xu, Xiangrong, Zhang, Yunqing, Zhang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10539569/
https://www.ncbi.nlm.nih.gov/pubmed/37781079
http://dx.doi.org/10.7150/jca.87545

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