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PEGylated exenatide injection (PB-119) improves beta-cell function and insulin resistance in treatment-naïve type 2 diabetes mellitus patients

Objective: PB-119, a PEGylated exenatide injection, is a once-weekly glucagon-like peptide-1 receptor agonist. In the present study, we aimed to evaluate the effects of PB-119 on insulin resistance and beta-cell function in Chinese patients with type 2 diabetes mellitus (T2DM) to uncover its antidia...

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Detalles Bibliográficos
Autores principales: Liu, Xu, Song, Ling, Zhang, Yuanhui, Li, Haiyan, Cui, Cheng, Liu, Dongyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10539604/
https://www.ncbi.nlm.nih.gov/pubmed/37781697
http://dx.doi.org/10.3389/fphar.2023.1088670