Isoxanthohumol improves obesity and glucose metabolism via inhibiting intestinal lipid absorption with a bloom of Akkermansia muciniphila in mice

OBJECTIVE: Polyphenols have health-promoting effects, such as improving insulin resistance. Isoxanthohumol (IX), a prenylated flavonoid found in beer hops, has been suggested to reduce obesity and insulin resistance; however, the mechanism remains unknown. METHODS: High-fat diet-fed mice were admini...

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Detalles Bibliográficos
Autores principales: Watanabe, Yoshiyuki, Fujisaka, Shiho, Morinaga, Yoshitomo, Watanabe, Shiro, Nawaz, Allah, Hatta, Hideki, Kado, Tomonobu, Nishimura, Ayumi, Bilal, Muhammad, Aslam, Muhammad Rahil, Honda, Keiko, Nakagawa, Yoshimi, Softic, Samir, Hirabayashi, Kenichi, Nakagawa, Takashi, Nagai, Yoshinori, Tobe, Kazuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10539672/
https://www.ncbi.nlm.nih.gov/pubmed/37709134
http://dx.doi.org/10.1016/j.molmet.2023.101797

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