RIT1 regulation of CNS lipids RIT1 deficiency Alters cerebral lipid metabolism and reduces white matter tract oligodendrocytes and conduction velocities()

Oligodendrocytes (OLs) generate lipid-rich myelin membranes that wrap axons to enable efficient transmission of electrical impulses. Using a RIT1 knockout mouse model and in situ high-resolution matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI) coupled with MS-based l...

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Detalles Bibliográficos
Autores principales: Wu, Lei, Wang, Fang, Moncman, Carole L., Pandey, Mritunjay, Clarke, Harrison A., Frazier, Hilaree N., Young, Lyndsay E.A., Gentry, Matthew S., Cai, Weikang, Thibault, Olivier, Sun, Ramon C., Andres, Douglas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10539968/
https://www.ncbi.nlm.nih.gov/pubmed/37780758
http://dx.doi.org/10.1016/j.heliyon.2023.e20384

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