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Dapagliflozin alleviates renal podocyte pyroptosis via regulation of the HO‑1/NLRP3 axis

Diabetic nephropathy is one of the most significant complications of diabetes, resulting in increased patient mortality. Dapagliflozin is an inhibitor of sodium-glucose cotransporter 2 that has an important protective effect on the kidney. Recent studies showed that pyroptosis is involved in the adv...

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Detalles Bibliográficos
Autores principales: Zhang, Zhenwang, Ni, Ping, Tang, Mingqiu, Song, Yi, Liu, Chao, Zhao, Baoqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10539996/
https://www.ncbi.nlm.nih.gov/pubmed/37711056
http://dx.doi.org/10.3892/mmr.2023.13087