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Internally tagged Vps10p-domain receptors reveal uptake of the neurotrophin BDNF

The Vps10p-domain (Vps10p-D) receptor family consists of Sortilin, SorLA, SorCS1, SorCS2, and SorCS3. They mediate internalization and intracellular sorting of specific cargo in various cell types, but underlying molecular determinants are incompletely understood. Deciphering the dynamic intracellul...

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Detalles Bibliográficos
Autores principales: Klein, Marcel, Failla, Antonio Virgilio, Hermey, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10540051/
https://www.ncbi.nlm.nih.gov/pubmed/37660918
http://dx.doi.org/10.1016/j.jbc.2023.105216