Cargando…

Coinfection of COVID-19 and Tuberculosis in Uganda

The clinical features and outcomes of tuberculosis (TB) and COVID-19 coinfection are not well established. This short report describes 11 people with TB/COVID-19 coinfection in Uganda. The mean age was 46.9 ± 14.5 years; eight (72.7%) were male and two (18.2%) were coinfected with HIV. All patients...

Descripción completa

Detalles Bibliográficos
Autores principales: Nuwagira, Edwin, Mpagama, Stellah G., Katusiime, Asumpta, Natamba, Bobson, Baluku, Joseph Baruch, Lai, Peggy S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Tropical Medicine and Hygiene 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10540107/
https://www.ncbi.nlm.nih.gov/pubmed/37094784
http://dx.doi.org/10.4269/ajtmh.22-0738
_version_ 1785113645485654016
author Nuwagira, Edwin
Mpagama, Stellah G.
Katusiime, Asumpta
Natamba, Bobson
Baluku, Joseph Baruch
Lai, Peggy S.
author_facet Nuwagira, Edwin
Mpagama, Stellah G.
Katusiime, Asumpta
Natamba, Bobson
Baluku, Joseph Baruch
Lai, Peggy S.
author_sort Nuwagira, Edwin
collection PubMed
description The clinical features and outcomes of tuberculosis (TB) and COVID-19 coinfection are not well established. This short report describes 11 people with TB/COVID-19 coinfection in Uganda. The mean age was 46.9 ± 14.5 years; eight (72.7%) were male and two (18.2%) were coinfected with HIV. All patients presented with cough whose median duration was 71.1 (interquartile range, 33.1, 109) days. Eight (72.7%) had mild COVID-19 whereas two (18.2%) died, including one with advanced HIV disease. All patients were treated with first-line anti-TB drugs and adjunct therapy for COVID-19 using national treatment guidelines. This report presents the possibility of the coexistence of the two diseases and calls for more vigilance, screening, and collective prevention measures for both COVID-19 and TB.
format Online
Article
Text
id pubmed-10540107
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher The American Society of Tropical Medicine and Hygiene
record_format MEDLINE/PubMed
spelling pubmed-105401072023-09-30 Coinfection of COVID-19 and Tuberculosis in Uganda Nuwagira, Edwin Mpagama, Stellah G. Katusiime, Asumpta Natamba, Bobson Baluku, Joseph Baruch Lai, Peggy S. Am J Trop Med Hyg Short Report The clinical features and outcomes of tuberculosis (TB) and COVID-19 coinfection are not well established. This short report describes 11 people with TB/COVID-19 coinfection in Uganda. The mean age was 46.9 ± 14.5 years; eight (72.7%) were male and two (18.2%) were coinfected with HIV. All patients presented with cough whose median duration was 71.1 (interquartile range, 33.1, 109) days. Eight (72.7%) had mild COVID-19 whereas two (18.2%) died, including one with advanced HIV disease. All patients were treated with first-line anti-TB drugs and adjunct therapy for COVID-19 using national treatment guidelines. This report presents the possibility of the coexistence of the two diseases and calls for more vigilance, screening, and collective prevention measures for both COVID-19 and TB. The American Society of Tropical Medicine and Hygiene 2023-04-24 2023-06 /pmc/articles/PMC10540107/ /pubmed/37094784 http://dx.doi.org/10.4269/ajtmh.22-0738 Text en © The author(s) https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution (CC-BY) License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Short Report
Nuwagira, Edwin
Mpagama, Stellah G.
Katusiime, Asumpta
Natamba, Bobson
Baluku, Joseph Baruch
Lai, Peggy S.
Coinfection of COVID-19 and Tuberculosis in Uganda
title Coinfection of COVID-19 and Tuberculosis in Uganda
title_full Coinfection of COVID-19 and Tuberculosis in Uganda
title_fullStr Coinfection of COVID-19 and Tuberculosis in Uganda
title_full_unstemmed Coinfection of COVID-19 and Tuberculosis in Uganda
title_short Coinfection of COVID-19 and Tuberculosis in Uganda
title_sort coinfection of covid-19 and tuberculosis in uganda
topic Short Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10540107/
https://www.ncbi.nlm.nih.gov/pubmed/37094784
http://dx.doi.org/10.4269/ajtmh.22-0738
work_keys_str_mv AT nuwagiraedwin coinfectionofcovid19andtuberculosisinuganda
AT mpagamastellahg coinfectionofcovid19andtuberculosisinuganda
AT katusiimeasumpta coinfectionofcovid19andtuberculosisinuganda
AT natambabobson coinfectionofcovid19andtuberculosisinuganda
AT balukujosephbaruch coinfectionofcovid19andtuberculosisinuganda
AT laipeggys coinfectionofcovid19andtuberculosisinuganda