Cargando…

Molecular landscapes of glioblastoma cell lines revealed a group of patients that do not benefit from WWOX tumor suppressor expression

INTRODUCTION: Glioblastoma (GBM) is notorious for its clinical and molecular heterogeneity, contributing to therapeutic failure and a grim prognosis. WWOX is one of the tumor suppressor genes important in nervous tissue or related pathologies, which was scarcely investigated in GBM for reliable asso...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kałuzińska-Kołat, Żaneta, Kołat, Damian, Kośla, Katarzyna, Płuciennik, Elżbieta, Bednarek, Andrzej K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10540236/ https://www.ncbi.nlm.nih.gov/pubmed/37781246 http://dx.doi.org/10.3389/fnins.2023.1260409

Ejemplares similares

Antineoplastic Nature of WWOX in Glioblastoma Is Mainly a Consequence of Reduced Cell Viability and Invasion
por: Kałuzińska-Kołat, Żaneta, et al.
Publicado: (2023)

LINC01137/miR-186-5p/WWOX: a novel axis identified from WWOX-related RNA interactome in bladder cancer
por: Kołat, Damian, et al.
Publicado: (2023)

Delineating the glioblastoma stemness by genes involved in cytoskeletal rearrangements and metabolic alterations
por: Kałuzińska-Kołat, Żaneta, et al.
Publicado: (2023)

In vitro and in silico assessment of the effect of WWOX expression on invasiveness pathways associated with AP-2 transcription factors in bladder cancer
por: Kałuzińska, Żaneta, et al.
Publicado: (2021)

WWOX Loses the Ability to Regulate Oncogenic AP-2γ and Synergizes with Tumor Suppressor AP-2α in High-Grade Bladder Cancer
por: Kołat, Damian, et al.
Publicado: (2021)

PLEK2, RRM2, GCSH: A Novel WWOX-Dependent Biomarker Triad of Glioblastoma at the Crossroads of Cytoskeleton Reorganization and Metabolism Alterations
por: Kałuzińska, Żaneta, et al.
Publicado: (2021)

Determination of WWOX Function in Modulating Cellular Pathways Activated by AP-2α and AP-2γ Transcription Factors in Bladder Cancer
por: Kołat, Damian, et al.
Publicado: (2022)

Fragile Gene WWOX Guides TFAP2A/TFAP2C-Dependent Actions Against Tumor Progression in Grade II Bladder Cancer
por: Kołat, Damian, et al.
Publicado: (2021)

Corrigendum: Fragile Gene WWOX Guides TFAP2A/TFAP2C-Dependent Actions Against Tumor Progression in Grade II Bladder Cancer
por: Kołat, Damian, et al.
Publicado: (2021)

The biological characteristics of transcription factors AP-2α and AP-2γ and their importance in various types of cancers
por: Kołat, Damian, et al.
Publicado: (2019)

Prognostic significance of AP-2α/γ targets as cancer therapeutics
por: Kołat, Damian, et al.
Publicado: (2022)

Functional genomics of AP-2α and AP-2γ in cancers: in silico study
por: Kołat, Damian, et al.
Publicado: (2020)

MicroRNAs: Their Role in Metastasis, Angiogenesis, and the Potential for Biomarker Utility in Bladder Carcinomas
por: Hammouz, Raneem Y., et al.
Publicado: (2021)

AP-2δ Is the Most Relevant Target of AP-2 Family-Focused Cancer Therapy and Affects Genome Organization
por: Kołat, Damian, et al.
Publicado: (2022)

Molecular analysis of WWOX expression correlation with proliferation and apoptosis in glioblastoma multiforme
por: Kosla, Katarzyna, et al.
Publicado: (2010)

The WWOX gene in brain development and pathology
por: Kośla, K, et al.
Publicado: (2020)

The WWOX/HIF1A Axis Downregulation Alters Glucose Metabolism and Predispose to Metabolic Disorders
por: Baryła, Izabela, et al.
Publicado: (2022)

The artificial oxygen carrier erythrocruorin—characteristics and potential significance in medicine
por: Kruczkowska, Weronika, et al.
Publicado: (2023)

WWOX Tumor Suppressor Gene in Breast Cancer, a Historical Perspective and Future Directions
por: Pospiech, Karolina, et al.
Publicado: (2018)

The WWOX Gene Influences Cellular Pathways in the Neuronal Differentiation of Human Neural Progenitor Cells
por: Kośla, Katarzyna, et al.
Publicado: (2019)

Exosomes as carriers transporting long non-coding RNAs: Molecular characteristics and their function in cancer
por: Kołat, Damian, et al.
Publicado: (2019)

TGFα-EGFR pathway in breast carcinogenesis, association with WWOX expression and estrogen activation
por: Pospiech, Karolina, et al.
Publicado: (2022)

WWOX modulates the gene expression profile in the T98G glioblastoma cell line rendering its phenotype less malignant
por: KOŚLA, KATARZYNA, et al.
Publicado: (2014)

WWOX and metabolic regulation in normal and pathological conditions
por: Baryła, Izabela, et al.
Publicado: (2022)

Identification of a novel association for the WWOX/HIF1A axis with gestational diabetes mellitus (GDM)
por: Baryla, Izabela, et al.
Publicado: (2021)

Do selected lifestyle parameters affect the severity and symptoms of COVID-19 among elderly patients? The retrospective evaluation of individuals from the STOP-COVID registry of the PoLoCOV study
por: Kapusta, Joanna, et al.
Publicado: (2023)

Pyroptosis-related signatures in bladder cancer prognosis and treatment—are we there yet?
por: Kołat, Damian, et al.
Publicado: (2022)

Alternating expression levels of WWOX tumor suppressor and cancer-related genes in patients with bladder cancer
por: PŁUCIENNIK, ELŻBIETA, et al.
Publicado: (2014)

Do COVID-19 Vaccinations Affect the Most Common Post-COVID Symptoms? Initial Data from the STOP-COVID Register–12-Month Follow-Up
por: Babicki, Mateusz, et al.
Publicado: (2023)

Doxorubicin—An Agent with Multiple Mechanisms of Anticancer Activity
por: Kciuk, Mateusz, et al.
Publicado: (2023)

PD-1/PD-L1 and DNA Damage Response in Cancer
por: Kciuk, Mateusz, et al.
Publicado: (2023)

Substances of Natural Origin in Medicine: Plants vs. Cancer
por: Gielecińska, Adrianna, et al.
Publicado: (2023)

Long-COVID Clinical Features and Risk Factors: A Retrospective Analysis of Patients from the STOP-COVID Registry of the PoLoCOV Study
por: Chudzik, Michał, et al.
Publicado: (2022)

Do the Successive Waves of SARS-CoV-2, Vaccination Status and Place of Infection Influence the Clinical Picture and COVID-19 Severity among Patients with Persistent Clinical Symptoms? The Retrospective Study of Patients from the STOP-COVID Registry of the PoLoCOV-Study
por: Chudzik, Michał, et al.
Publicado: (2022)

Carboxymethyl Chitosan Hydrogels for Effective Wound Healing—An Animal Study
por: Kłosiński, Karol Kamil, et al.
Publicado: (2023)

WWOX expression in colorectal cancer—a real-time quantitative RT-PCR study
por: Żelazowski, Maciej Jakub, et al.
Publicado: (2011)

Biocompatibility and Mechanical Properties of Carboxymethyl Chitosan Hydrogels
por: Kłosiński, Karol K., et al.
Publicado: (2022)

A Novel Set of WNT Pathway Effectors as a Predictive Marker of Uterine Corpus Endometrial Carcinoma–Study Based on Weighted Co-expression Matrices
por: Kośla, Katarzyna, et al.
Publicado: (2019)

Tumor Suppressor WWOX and p53 Alterations and Drug Resistance in Glioblastomas
por: Chiang, Ming-Fu, et al.
Publicado: (2013)

Whether and what abnormalities we find in ECG records and 24-hour Holter ECG in patients after COVID-19 without hospitalization with cardiac damage
por: Chudzik, M, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_l04nrqqcaakn5pn3l9pnqjf3sa