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Condensate cooperativity underlies transgenerational gene silencing
Biomolecular condensates have been shown to interact in vivo, yet it is unclear whether these interactions are functionally meaningful. Here, we demonstrate that cooperativity between two distinct condensates—germ granules and P bodies—is required for transgenerational gene silencing in C. elegans....
Autores principales: | Zhenzhen, Du, Shi, Kun, Brown, Jordan S., He, Tao, Wei-Sheng, Wu, Zhang, Ying, Heng-Chi, Lee, Zhang, Donglei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10540246/ https://www.ncbi.nlm.nih.gov/pubmed/37505984 http://dx.doi.org/10.1016/j.celrep.2023.112859 |
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