Guanidyl-Rich Poly(β Amino Ester)s for Universal Functional Cytosolic Protein Delivery and Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) Cas9 Ribonucleoprotein Based Gene Editing

[Image: see text] Protein therapeutics are highly promising for complex disease treatment. However, the lack of ideal delivery vectors impedes their clinical use, especially the carriers for in vivo delivery of functional cytosolic protein. In this study, we modified poly(β amino ester)s (PAEs) with...

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Detalles Bibliográficos
Autores principales: Wang, Xianqing, Li, Yinghao, Wang, Xi, Sandoval, Dario M., He, Zhonglei, A, Sigen, Sáez, Irene Lara, Wang, Wenxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10540258/
https://www.ncbi.nlm.nih.gov/pubmed/37669145
http://dx.doi.org/10.1021/acsnano.3c03269

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