A loss-of-function mutation in human Oxidation Resistance 1 disrupts the spatial–temporal regulation of histone arginine methylation in neurodevelopment

BACKGROUND: Oxidation Resistance 1 (OXR1) gene is a highly conserved gene of the TLDc domain-containing family. OXR1 is involved in fundamental biological and cellular processes, including DNA damage response, antioxidant pathways, cell cycle, neuronal protection, and arginine methylation. In 2019,...

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Detalles Bibliográficos
Autores principales: Lin, Xiaolin, Wang, Wei, Yang, Mingyi, Damseh, Nadirah, de Sousa, Mirta Mittelstedt Leal, Jacob, Fadi, Lång, Anna, Kristiansen, Elise, Pannone, Marco, Kissova, Miroslava, Almaas, Runar, Kuśnierczyk, Anna, Siller, Richard, Shahrour, Maher, Al-Ashhab, Motee, Abu-Libdeh, Bassam, Tang, Wannan, Slupphaug, Geir, Elpeleg, Orly, Bøe, Stig Ove, Eide, Lars, Sullivan, Gareth J., Rinholm, Johanne Egge, Song, Hongjun, Ming, Guo-li, van Loon, Barbara, Edvardson, Simon, Ye, Jing, Bjørås, Magnar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10540402/
https://www.ncbi.nlm.nih.gov/pubmed/37773136
http://dx.doi.org/10.1186/s13059-023-03037-1

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