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A preliminary study of phosphodiesterases and adenylyl cyclase signaling pathway on red blood cell deformability of sickle cell patients

Sickle cell disease (SCD) is an inherited hemoglobinopathy characterized by chronic anemia, intravascular hemolysis, and the occurrence of vaso-occlusive crises due to the mechanical obstruction of the microcirculation by poorly deformable red blood cells (RBCs). RBC deformability is a key factor in...

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Detalles Bibliográficos
Autores principales:	Goksel, Evrim, Ugurel, Elif, Nader, Elie, Boisson, Camille, Muniansi, Ingrid, Joly, Philippe, Renoux, Celine, Gauthier, Alexandra, Connes, Philippe, Yalcin, Ozlem
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10540448/ https://www.ncbi.nlm.nih.gov/pubmed/37781231 http://dx.doi.org/10.3389/fphys.2023.1215835

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