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Increased reports of severe myocarditis associated with enterovirus infection in neonates, United Kingdom, 27 June 2022 to 26 April 2023

Enteroviruses are a common cause of seasonal childhood infections. The vast majority of enterovirus infections are mild and self-limiting, although neonates can sometimes develop severe disease. Myocarditis is a rare complication of enterovirus infection. Between June 2022 and April 2023, twenty cas...

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Autores principales: Singanayagam, Anika, Moore, Catherine, Froude, Susannah, Celma, Cristina, Stowe, Julia, Hani, Erjola, Ng, Khuen Foong, Muir, Peter, Roderick, Marion, Cottrell, Simon, Bibby, David F., Vipond, Barry, Gillett, Sophie, Davis, Peter J., Gibb, Jack, Barry, Mai, Harris, Phillippa, Rowley, Frances, Song, Jiao, Shankar, Ananda Giri, McMichael, Danielle, Cohen, Jonathan M., Manian, Abirami, Harvey, Ciaran, Primrose, Louise Shaw, Wilson, Stefanie, Bradley, Declan T., Paranthaman, Karthik, Beard, Stuart, Zambon, Maria, Ramsay, Mary, Saliba, Vanessa, Ladhani, Shamez, Williams, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Centre for Disease Prevention and Control (ECDC) 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10540513/
https://www.ncbi.nlm.nih.gov/pubmed/37768558
http://dx.doi.org/10.2807/1560-7917.ES.2023.28.39.2300313
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author Singanayagam, Anika
Moore, Catherine
Froude, Susannah
Celma, Cristina
Stowe, Julia
Hani, Erjola
Ng, Khuen Foong
Muir, Peter
Roderick, Marion
Cottrell, Simon
Bibby, David F.
Vipond, Barry
Gillett, Sophie
Davis, Peter J.
Gibb, Jack
Barry, Mai
Harris, Phillippa
Rowley, Frances
Song, Jiao
Shankar, Ananda Giri
McMichael, Danielle
Cohen, Jonathan M.
Manian, Abirami
Harvey, Ciaran
Primrose, Louise Shaw
Wilson, Stefanie
Bradley, Declan T.
Paranthaman, Karthik
Beard, Stuart
Zambon, Maria
Ramsay, Mary
Saliba, Vanessa
Ladhani, Shamez
Williams, Christopher
author_facet Singanayagam, Anika
Moore, Catherine
Froude, Susannah
Celma, Cristina
Stowe, Julia
Hani, Erjola
Ng, Khuen Foong
Muir, Peter
Roderick, Marion
Cottrell, Simon
Bibby, David F.
Vipond, Barry
Gillett, Sophie
Davis, Peter J.
Gibb, Jack
Barry, Mai
Harris, Phillippa
Rowley, Frances
Song, Jiao
Shankar, Ananda Giri
McMichael, Danielle
Cohen, Jonathan M.
Manian, Abirami
Harvey, Ciaran
Primrose, Louise Shaw
Wilson, Stefanie
Bradley, Declan T.
Paranthaman, Karthik
Beard, Stuart
Zambon, Maria
Ramsay, Mary
Saliba, Vanessa
Ladhani, Shamez
Williams, Christopher
author_sort Singanayagam, Anika
collection PubMed
description Enteroviruses are a common cause of seasonal childhood infections. The vast majority of enterovirus infections are mild and self-limiting, although neonates can sometimes develop severe disease. Myocarditis is a rare complication of enterovirus infection. Between June 2022 and April 2023, twenty cases of severe neonatal enteroviral myocarditis caused by coxsackie B viruses were reported in the United Kingdom. Sixteen required critical care support and two died. Enterovirus PCR on whole blood was the most sensitive diagnostic test. We describe the initial public health investigation into this cluster and aim to raise awareness among paediatricians, laboratories and public health specialists.
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spelling pubmed-105405132023-09-30 Increased reports of severe myocarditis associated with enterovirus infection in neonates, United Kingdom, 27 June 2022 to 26 April 2023 Singanayagam, Anika Moore, Catherine Froude, Susannah Celma, Cristina Stowe, Julia Hani, Erjola Ng, Khuen Foong Muir, Peter Roderick, Marion Cottrell, Simon Bibby, David F. Vipond, Barry Gillett, Sophie Davis, Peter J. Gibb, Jack Barry, Mai Harris, Phillippa Rowley, Frances Song, Jiao Shankar, Ananda Giri McMichael, Danielle Cohen, Jonathan M. Manian, Abirami Harvey, Ciaran Primrose, Louise Shaw Wilson, Stefanie Bradley, Declan T. Paranthaman, Karthik Beard, Stuart Zambon, Maria Ramsay, Mary Saliba, Vanessa Ladhani, Shamez Williams, Christopher Euro Surveill Outbreaks Enteroviruses are a common cause of seasonal childhood infections. The vast majority of enterovirus infections are mild and self-limiting, although neonates can sometimes develop severe disease. Myocarditis is a rare complication of enterovirus infection. Between June 2022 and April 2023, twenty cases of severe neonatal enteroviral myocarditis caused by coxsackie B viruses were reported in the United Kingdom. Sixteen required critical care support and two died. Enterovirus PCR on whole blood was the most sensitive diagnostic test. We describe the initial public health investigation into this cluster and aim to raise awareness among paediatricians, laboratories and public health specialists. European Centre for Disease Prevention and Control (ECDC) 2023-09-28 /pmc/articles/PMC10540513/ /pubmed/37768558 http://dx.doi.org/10.2807/1560-7917.ES.2023.28.39.2300313 Text en This article is copyright of the authors or their affiliated institutions, 2023. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made.
spellingShingle Outbreaks
Singanayagam, Anika
Moore, Catherine
Froude, Susannah
Celma, Cristina
Stowe, Julia
Hani, Erjola
Ng, Khuen Foong
Muir, Peter
Roderick, Marion
Cottrell, Simon
Bibby, David F.
Vipond, Barry
Gillett, Sophie
Davis, Peter J.
Gibb, Jack
Barry, Mai
Harris, Phillippa
Rowley, Frances
Song, Jiao
Shankar, Ananda Giri
McMichael, Danielle
Cohen, Jonathan M.
Manian, Abirami
Harvey, Ciaran
Primrose, Louise Shaw
Wilson, Stefanie
Bradley, Declan T.
Paranthaman, Karthik
Beard, Stuart
Zambon, Maria
Ramsay, Mary
Saliba, Vanessa
Ladhani, Shamez
Williams, Christopher
Increased reports of severe myocarditis associated with enterovirus infection in neonates, United Kingdom, 27 June 2022 to 26 April 2023
title Increased reports of severe myocarditis associated with enterovirus infection in neonates, United Kingdom, 27 June 2022 to 26 April 2023
title_full Increased reports of severe myocarditis associated with enterovirus infection in neonates, United Kingdom, 27 June 2022 to 26 April 2023
title_fullStr Increased reports of severe myocarditis associated with enterovirus infection in neonates, United Kingdom, 27 June 2022 to 26 April 2023
title_full_unstemmed Increased reports of severe myocarditis associated with enterovirus infection in neonates, United Kingdom, 27 June 2022 to 26 April 2023
title_short Increased reports of severe myocarditis associated with enterovirus infection in neonates, United Kingdom, 27 June 2022 to 26 April 2023
title_sort increased reports of severe myocarditis associated with enterovirus infection in neonates, united kingdom, 27 june 2022 to 26 april 2023
topic Outbreaks
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10540513/
https://www.ncbi.nlm.nih.gov/pubmed/37768558
http://dx.doi.org/10.2807/1560-7917.ES.2023.28.39.2300313
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