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Treatment of esophageal leakages with the Microtech(®)-VAC-Stent: a monocentric early experience of three cases

BACKGROUND: Endoscopic approaches in the treatment of transmural esophageal defects, either after esophageal resection or due to perforation, have demonstrated convincing feasibility. Surgical options are limited and associated with high morbidity and mortality rates. Currently, internal endoscopic...

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Autores principales: Klose, Michelle A., Walldorf, Jens, Damm, Marko, Krug, Sebastian, Klose, Johannes, Ronellenfitsch, Ulrich, Kleeff, Joerg, Michl, Patrick, Rosendahl, Jonas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10540572/
https://www.ncbi.nlm.nih.gov/pubmed/37779920
http://dx.doi.org/10.1177/26317745231200312
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author Klose, Michelle A.
Walldorf, Jens
Damm, Marko
Krug, Sebastian
Klose, Johannes
Ronellenfitsch, Ulrich
Kleeff, Joerg
Michl, Patrick
Rosendahl, Jonas
author_facet Klose, Michelle A.
Walldorf, Jens
Damm, Marko
Krug, Sebastian
Klose, Johannes
Ronellenfitsch, Ulrich
Kleeff, Joerg
Michl, Patrick
Rosendahl, Jonas
author_sort Klose, Michelle A.
collection PubMed
description BACKGROUND: Endoscopic approaches in the treatment of transmural esophageal defects, either after esophageal resection or due to perforation, have demonstrated convincing feasibility. Surgical options are limited and associated with high morbidity and mortality rates. Currently, internal endoscopic drainage with pigtail stents, self-expanding metal stent (SEMS), or endoscopic vacuum therapy (EVT) are options for first-line treatment. Here, we report the outcome of the recently developed combination of SEMS and EVT using the endoscopic Microtech(®)-VAC-Stent (EVS). METHODS: Between June and July 2022, three consecutive patients (one female and two males) with esophageal transmural defects were treated with the Microtech(®)-VAC-Stent. Two patients suffered from an anastomotic leak after oncologic gastroesophageal surgery, and one patient presented with esophageal perforation due to Boerhaave syndrome. RESULTS: Three consecutive patients were successfully treated with EVS. In one patient, one EVS treatment was sufficient, whereas the other two patients needed two and six EVS exchanges. Exchanges were scheduled every 7 days and no procedural adverse events were observed. CONCLUSION: In line with the former case series, EVS therapy is a promising new approach for the treatment of esophageal leaks. Exchange of the EVS seems feasible every 7 days reducing interventions for the individual patient. Prospective studies comparing EVS with other endoscopic therapies are needed to define the best therapeutic approach.
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spelling pubmed-105405722023-09-30 Treatment of esophageal leakages with the Microtech(®)-VAC-Stent: a monocentric early experience of three cases Klose, Michelle A. Walldorf, Jens Damm, Marko Krug, Sebastian Klose, Johannes Ronellenfitsch, Ulrich Kleeff, Joerg Michl, Patrick Rosendahl, Jonas Ther Adv Gastrointest Endosc Original Research BACKGROUND: Endoscopic approaches in the treatment of transmural esophageal defects, either after esophageal resection or due to perforation, have demonstrated convincing feasibility. Surgical options are limited and associated with high morbidity and mortality rates. Currently, internal endoscopic drainage with pigtail stents, self-expanding metal stent (SEMS), or endoscopic vacuum therapy (EVT) are options for first-line treatment. Here, we report the outcome of the recently developed combination of SEMS and EVT using the endoscopic Microtech(®)-VAC-Stent (EVS). METHODS: Between June and July 2022, three consecutive patients (one female and two males) with esophageal transmural defects were treated with the Microtech(®)-VAC-Stent. Two patients suffered from an anastomotic leak after oncologic gastroesophageal surgery, and one patient presented with esophageal perforation due to Boerhaave syndrome. RESULTS: Three consecutive patients were successfully treated with EVS. In one patient, one EVS treatment was sufficient, whereas the other two patients needed two and six EVS exchanges. Exchanges were scheduled every 7 days and no procedural adverse events were observed. CONCLUSION: In line with the former case series, EVS therapy is a promising new approach for the treatment of esophageal leaks. Exchange of the EVS seems feasible every 7 days reducing interventions for the individual patient. Prospective studies comparing EVS with other endoscopic therapies are needed to define the best therapeutic approach. SAGE Publications 2023-09-28 /pmc/articles/PMC10540572/ /pubmed/37779920 http://dx.doi.org/10.1177/26317745231200312 Text en © The Author(s), 2023 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Original Research
Klose, Michelle A.
Walldorf, Jens
Damm, Marko
Krug, Sebastian
Klose, Johannes
Ronellenfitsch, Ulrich
Kleeff, Joerg
Michl, Patrick
Rosendahl, Jonas
Treatment of esophageal leakages with the Microtech(®)-VAC-Stent: a monocentric early experience of three cases
title Treatment of esophageal leakages with the Microtech(®)-VAC-Stent: a monocentric early experience of three cases
title_full Treatment of esophageal leakages with the Microtech(®)-VAC-Stent: a monocentric early experience of three cases
title_fullStr Treatment of esophageal leakages with the Microtech(®)-VAC-Stent: a monocentric early experience of three cases
title_full_unstemmed Treatment of esophageal leakages with the Microtech(®)-VAC-Stent: a monocentric early experience of three cases
title_short Treatment of esophageal leakages with the Microtech(®)-VAC-Stent: a monocentric early experience of three cases
title_sort treatment of esophageal leakages with the microtech(®)-vac-stent: a monocentric early experience of three cases
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10540572/
https://www.ncbi.nlm.nih.gov/pubmed/37779920
http://dx.doi.org/10.1177/26317745231200312
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