Exploring the mechanism of metformin action in Alzheimer’s disease and type 2 diabetes based on network pharmacology, molecular docking, and molecular dynamic simulation

BACKGROUND: Metformin, which has been shown to be highly effective in treating type 2 diabetes (T2D), is also believed to be valuable for Alzheimer’s disease (AD). Computer simulation techniques have emerged as an innovative approach to explore mechanisms. OBJECTIVE: To study the potential mechanism...

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Detalles Bibliográficos
Autores principales: Shi, Xin, Li, Lingling, Liu, Zhiyao, Wang, Fangqi, Huang, Hailiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10540612/
https://www.ncbi.nlm.nih.gov/pubmed/37780174
http://dx.doi.org/10.1177/20420188231187493

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10540612/
https://www.ncbi.nlm.nih.gov/pubmed/37780174
http://dx.doi.org/10.1177/20420188231187493

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